Washington University in Saint Louis
University of California - Santa Barbara
University of California - Berkeley
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Project Title:
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Integrated Nanosystem for Diagnosis and Therapy
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Project Number:
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HL080729
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Web Site:
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http://www.nhlbi-pen.info/
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PI:
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Karen L. Wooley
James S. McDonnell Distinguished University Professor in Arts & Sciences
Department of Chemistry
Washington University in St. Louis
One Brookings Drive, CB 1134
St. Louis, MO 63130-4899
phone: +1 314 935-7136
fax: +1 314 935-9844
klwooley@wustl.edu
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Budget:
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$12 Million ca.
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Consortium:
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Washington University in Saint Louis
University of California - Santa Barbara
University of California - Berkley
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Aims:
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The central mission of this project is to develop a group of well-characterized and versatile nanoscale agents that can be assembled, labeled, targeted, filled, and activated as needed for the diagnosis and treatment of various diseases of relevance to the National Heart Lung and Blood Institute (NHLBI).
The overall experimental strategy is focus on biological models of acute pulmonary and systemic vascular injury (in vitro and in vivo) to demonstrate the effectiveness of these agents. Acute vascular injury and inflammation have been chosen as general targets since they affect tissues broadly, including those of the lung and cardiovascular system.
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More Information
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